Facility Impact

Publications

  1. Peptide IRW upregulates ACE2 in spontaneously hypertensive rats via dopamine/D1R signaling pathway. J. Adv. Res. (2025). https://doi.org/10.1016/j.jare.2025.11.020
  2. Novel Hsp90 inhibitors as leads for the development of radiotheragnostics for Meitner-Auger electron therapy. Bioorg. Chem. (2026). https://doi.org/10.1016/j.bioorg.2026.109522
  3. Identification of novel umami peptides with anti-inflammatory and antioxidant effects in spent hen protein hydrolysate. Food Chem. (2025). https://doi.org/10.1016/j.foodchem.2025.147664
  4. Brain and neural cell type proteomics reveal extracellular matrix proteins enriched in progressive multiple sclerosis. Nat. Commun. (2025). https://doi.org/10.1038/s41467-025-68118-0
  5. The ER thioredoxin-related transmembrane protein TMX2 controls redox-mediated tethering of ER-mitochondria contacts. Cell Rep. (2025). https://doi.org/10.1016/j.celrep.2025.116486
  6. Gangliosides modulate the secretion of extracellular vesicles and their misfolded protein cargo. Sci. Adv. (2025). https://doi.org/10.1126/sciadv.ady5212
  7. Structural and functional analyses of SARS-CoV-2 Nsp3 and its specific interactions with the 5' UTR of the viral genome. Microbiol. Spectr. (2024). https://doi.org/10.1128/spectrum.02871-24
  8. Protein corona composition modulates uptake of polymeric micelles by colorectal cancer cells. Nanoscale Adv. (2024). https://doi.org/10.1039/d4na01085j
  9. Comparative structural insights of X protein across species and the "lost" BH3-like domain that may explain the absence of hepatocellular carcinoma in birds. Infect. Genet. Evol. (2025). https://doi.org/10.1016/j.meegid.2025.105777
  10. Investigation of CD36 interactome provides insights into multimolecular complexes necessary for anti-angiogenic signalling. bioRxiv (2025). https://doi.org/10.1101/2025.07.15.664851
  11. New molecular components of high and low affinity iron import systems in Drosophila. Nat. Commun. (2025). https://doi.org/10.1038/s41467-025-60758-6
  12. Mechanism of Inhibition of the Active Triphosphate Form of 2'-α-Fluoro,2'-β-bromouridine against Yellow Fever Virus RNA-Dependent RNA Polymerase. ACS Infect. Dis. (2025). https://doi.org/10.1021/acsinfecdis.5c00086
  13. The Novel Lipid Emulsion Vegaven Is Well Tolerated and Elicits Distinct Biological Actions Compared With a Mixed-Oil Lipid Emulsion Containing Fish Oil: A Parenteral Nutrition Trial in Piglets. J. Nutr. (2024). https://doi.org/10.1016/j.tjnut.2024.10.047
  14. Differential substrate preferences IN ACTINOBACTERIAL protein O-MANNOSYLTRANSFERASES and alteration of protein-O-MANNOSYLATION by choice of secretion pathway. Glycobiology (2024). https://doi.org/10.1093/glycob/cwae095
  15. Histamine stimulates human microglia to alter cellular prion protein expression via the HRH2 histamine receptor. Sci. Rep. (2024). https://doi.org/10.1038/s41598-024-75982-1
  16. Antioxidant and anti-inflammatory peptides in dry-fermented sausages fermented with Staphylococcus simulans QB7. Food Funct. (2024). https://doi.org/10.1039/d4fo03659j
  17. N-Terminomic Identification of Intracellular MMP-2 Substrates in Cardiac Tissue. J. Proteome Res. (2024). https://doi.org/10.1021/acs.jproteome.3c00755
  18. First-Generation Radiolabeled Cyclic Peptides for Molecular Imaging of Platelet-Derived Growth Factor Receptor α. Mol. Pharmaceutics (2024). https://doi.org/10.1021/acs.molpharmaceut.4c00549
  19. Comparing the BAD Protein Interactomes in 2D and 3D Cell Culture Using Proximity Labeling. J. Proteome Res. (2024). https://doi.org/10.1021/acs.jproteome.4c00111
  20. Loss of ADAM15 in female mice does not worsen pressure overload cardiomyopathy, independent of ovarian hormones. Am. J. Physiol. Heart Circ. Physiol. (2024). https://doi.org/10.1152/ajpheart.00116.2024
  21. Not So Rare: Diseases Based on Mutant Proteins Controlling Endoplasmic Reticulum-Mitochondria Contact (MERC) Tethering. Contact (2024). https://doi.org/10.1177/25152564241261228
  22. Drosophila Evi5 is a critical regulator of intracellular iron transport via transferrin and ferritin interactions. Nat. Commun. (2024). https://doi.org/10.1038/s41467-024-48165-9
  23. Hsp90 inhibition leads to an increase in surface expression of multiple immunological receptors in cancer cells. Front. Mol. Biosci. 11, 1334876 (2024). https://doi.org/10.3389/fmolb.2024.1334876
  24. An acetyltransferase effector conserved across Legionella species targets the eukaryotic eIF3 complex to modulate protein translation. mBio (2024). https://doi.org/10.1128/mbio.03221-23
  25. Calreticulin: Endoplasmic reticulum Ca(2+) gatekeeper. J. Cell. Mol. Med. (2023). https://doi.org/10.1111/jcmm.17839
  26. Membranes are functionalized by a proteolipid code. BMC Biol. (2024). https://doi.org/10.1186/s12915-024-01849-6
  27. Application of N-Terminal Labeling Methods Provide Novel Insights into Endoproteolysis of the Prion Protein in Vivo. ACS Chem. Neurosci. (2023). https://doi.org/10.1021/acschemneuro.3c00533
  28. Could a Non-Cellular Molecular Interactome in the Blood Circulation Influence Pathogens' Infectivity? Cells 12, 1699 (2023). https://doi.org/10.3390/cells12131699
  29. Toward an experimental system for the examination of protein mannosylation in Actinobacteria. Glycobiology (2023). https://doi.org/10.1093/glycob/cwad023
  30. Mast Cell Proteases Cleave Prion Proteins and a Recombinant Ig against PrP Can Activate Human Mast Cells. J. Immunol. (2023). https://doi.org/10.4049/jimmunol.2200726
  31. Douchi Peptides VY and SFLLR Improve Glucose Homeostasis and Gut Dysbacteriosis in High-Fat Diet-Induced Insulin Resistant Mice. Mol. Nutr. Food Res. (2023). https://doi.org/10.1002/mnfr.202200681
  32. Identification of Human Host Substrates of the SARS-CoV-2 M(pro) and PL(pro) Using Subtiligase N-Terminomics. ACS Infect. Dis. (2023). https://doi.org/10.1021/acsinfecdis.2c00458
  33. Amanita muscaria extract potentiates production of proinflammatory cytokines by dsRNA-activated human microglia. Front. Pharmacol. 14, 1102465 (2023). https://doi.org/10.3389/fphar.2023.1102465
  34. Casein Hydrolysate Alleviates Adipose Chronic Inflammation in High Fat-Diet Induced Obese C57BL/6J Mice through MAPK Pathway. Nutrients 15, 1813 (2023). https://doi.org/10.3390/nu15081813
  35. Monomer and dimer structures of cytochrome bo(3) ubiquinol oxidase from Escherichia coli. Protein Sci. (2023). https://doi.org/10.1002/pro.4616
  36. Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF): An Emerging Therapeutic Target for Neurodegenerative Disorders. Cells 12, 1032 (2023). https://doi.org/10.3390/cells12071032
  37. Sodium butyrate supresses malignant human mast cell proliferation, downregulates expression of KIT and promotes differentiation. Front. Allergy 4, 1109717 (2023). https://doi.org/10.3389/falgy.2023.1109717
  38. Peptidomics Study of Plant-Based Meat Analogs as a Source of Bioactive Peptides. Foods 12, 1061 (2023). https://doi.org/10.3390/foods12051061
  39. CaspSites: A Database and Web Application for Experimentally Observed Human Caspase Substrates Using N-Terminomics. J. Proteome Res. (2023). https://doi.org/10.1021/acs.jproteome.2c00620
  40. The endoplasmic reticulum kinase PERK interacts with the oxidoreductase ERO1 to metabolically adapt mitochondria. Cell Rep. (2022). https://doi.org/10.1016/j.celrep.2022.111899
  41. Distinct Molecular Features of NleG Type 3 Secreted Effectors Allow for Different Roles during Citrobacter rodentium Infection in Mice. Infect. Immun. (2022). https://doi.org/10.1128/iai.00505-22
  42. Soybean-Derived Tripeptide Leu-Ser-Trp (LSW) Protects Human Vascular Endothelial Cells from TNFα-Induced Oxidative Stress and Inflammation via Modulating TNFα Receptors and SIRT1. Foods 11, 3372 (2022). https://doi.org/10.3390/foods11213372
  43. Structurally Modified Bioactive Peptide Inhibits SARS-CoV-2 Lentiviral Particles Expression. Pharmaceutics 14, 2045 (2022). https://doi.org/10.3390/pharmaceutics14102045
  44. Could Endogenous Glucocorticoids Influence SARS-CoV-2 Infectivity? Cells 11, 2955 (2022). https://doi.org/10.3390/cells11192955
  45. Arginine-Containing Peptides Derived from Walnut Protein Against Cognitive and Memory Impairment in Scopolamine-Induced Zebrafish: Design, Release, and Neuroprotection. J. Agric. Food Chem. (2022). https://doi.org/10.1021/acs.jafc.2c05104
  46. DEAD box 1 (DDX1) protein binds to and protects cytoplasmic stress response mRNAs in cells exposed to oxidative stress. J. Biol. Chem. (2022). https://doi.org/10.1016/j.jbc.2022.102180
  47. Peptides GWN and GW protect kidney cells against Dasatinib induced mitochondrial injury in a SIRT1 dependent manner. Food Chem. Mol. Sci. (2022). https://doi.org/10.1016/j.fochms.2021.100069
  48. Glucocorticoids Bind to SARS-CoV-2 S1 at Multiple Sites Causing Cooperative Inhibition of SARS-CoV-2 S1 Interaction With ACE2. Front. Immunol. 13, 906687 (2022). https://doi.org/10.3389/fimmu.2022.906687
  49. DDX41 is required for cGAS-STING activation against DNA virus infection. Cell Rep. (2022). https://doi.org/10.1016/j.celrep.2022.110856
  50. Matrix metalloproteinase-2 mediates ribosomal RNA transcription by cleaving nucleolar histones. FEBS J. (2021). https://doi.org/10.1111/febs.16061
  51. Deorphanizing Caspase-3 and Caspase-9 Substrates In and Out of Apoptosis with Deep Substrate Profiling. ACS Chem. Biol. (2021). https://doi.org/10.1021/acschembio.1c00456
  52. Peptide-Modified Surfaces for Binding Carbamylated Proteins from Plasma. Langmuir (2021). https://doi.org/10.1021/acs.langmuir.1c01783
  53. Amino Acids 785, 787 of the Na(+)/H(+) Exchanger Cytoplasmic Tail Modulate Protein Activity and Tail Conformation. Int. J. Mol. Sci. 22, 11349 (2021). https://doi.org/10.3390/ijms222111349
  54. H(2)pyhox - Octadentate Bis(pyridyloxine). Inorg. Chem. (2021). https://doi.org/10.1021/acs.inorgchem.1c01412
  55. Amyotrophic Lateral Sclerosis (ALS): Stressed by Dysfunctional Mitochondria-Endoplasmic Reticulum Contacts (MERCs). Cells 10, 1789 (2021). https://doi.org/10.3390/cells10071789
  56. Purification and identification of novel ACE inhibitory and ACE2 upregulating peptides from spent hen muscle proteins. Food Chem. (2021). https://doi.org/10.1016/j.foodchem.2020.128867
  57. Peptide Analogues of VPP and IPP with Improved Glucose Uptake Activity in L6 Myotubes can be Released from Cereal Proteins. J. Agric. Food Chem. (2021). https://doi.org/10.1021/acs.jafc.1c00587
  58. Choice of Lipid Emulsion Determines Inflammation of the Gut-Liver Axis, Incretin Profile, and Insulin Signaling in a Murine Model of Total Parenteral Nutrition. Mol. Nutr. Food Res. (2020). https://doi.org/10.1002/mnfr.202000412
  59. Spent Hen Muscle Protein-Derived RAS Regulating Peptides Show Antioxidant Activity in Vascular Cells. Antioxidants 10, 290 (2021). https://doi.org/10.3390/antiox10020290
  60. Tripeptide IRW Upregulates NAMPT Protein Levels in Cells and Obese C57BL/6J Mice. J. Agric. Food Chem. (2021). https://doi.org/10.1021/acs.jafc.0c07831
  61. Spent Hen Protein Hydrolysate with Good Gastrointestinal Stability and Permeability in Caco-2 Cells Shows Antihypertensive Activity in SHR. Foods 9, 1384 (2020). https://doi.org/10.3390/foods9101384
  62. Phosvitin Derived Phospho-Peptides Show Better Osteogenic Potential than Intact Phosvitin in MC3T3-E1 Osteoblastic Cells. Nutrients 12, 2998 (2020). https://doi.org/10.3390/nu12102998
  63. Calsequestrin. Structure, function, and evolution. Cell Calcium (2020). https://doi.org/10.1016/j.ceca.2020.102242
  64. Biology of Tissue Inhibitor of Metalloproteinase 3 (TIMP3), and Its Therapeutic Implications in Cardiovascular Pathology. Front. Physiol. 11, 661 (2020). https://doi.org/10.3389/fphys.2020.00661
  65. Independent inhibition of the polymerase and deubiquitinase activities of the Crimean-Congo Hemorrhagic Fever Virus full-length L-protein. PLoS Negl. Trop. Dis. 14, e0008283 (2020). https://doi.org/10.1371/journal.pntd.0008283
  66. Regulatory Effects of a Pea-Derived Peptide Leu-Arg-Trp (LRW) on Dysfunction of Rat Aortic Vascular Smooth Muscle Cells against Angiotensin II Stimulation. J. Agric. Food Chem. (2020). https://doi.org/10.1021/acs.jafc.0c00028
  67. Amino Acids 563-566 of the Na(+)/H(+) Exchanger Isoform 1 C-Terminal Cytosolic Tail Prevent Protein Degradation and Stabilize Protein Expression and Activity. Int. J. Mol. Sci. 21, 1737 (2020). https://doi.org/10.3390/ijms21051737
  68. Expression and detergent free purification and reconstitution of the plant plasma membrane Na(+)/H(+) antiporter SOS1 overexpressed in Pichia pastoris. Biochim. Biophys. Acta Biomembr. (2020). https://doi.org/10.1016/j.bbamem.2019.183111
  69. Polymorphisms in the Most Oncolytic Reovirus Strain Confer Enhanced Cell Attachment, Transcription, and Single-Step Replication Kinetics. J. Virol. (2020). https://doi.org/10.1128/JVI.01937-19
  70. Lipid Emulsion Containing High Amounts of n3 Fatty Acids (Omegaven) as Opposed to n6 Fatty Acids (Intralipid) Preserves Insulin Signaling and Glucose Uptake in Perfused Rat Hearts. Anesth. Analg. (2019). https://doi.org/10.1213/ANE.0000000000004295